Elucidating the mechanism of cellular
For each subdivision of human knowledge, the text identifies its fundamental concepts, principles, mysteries, and misunderstandings.
Additionally, the researchers hypothesize, lithium acts to block the serotonin “transporter” protein.Researchers will use PET imaging to determine how lithium acts on the transmitter serotonin to provide therapeutic benefit in patients with bipolar disease.Lithium has been used for more than two decades to treat bipolar disorder, primarily by preventing or lessening depressive episodes and preventing patients’ tendencies toward suicide.One objective is to understand the mechanism at the molecular, cellular, circuit, and system level.Knowledge obtained from such studies will provide a better understanding of sleep disorders, absence seizures, and conditions of impaired control of consciousness.2016-10-03 The Nobel Assembly at Karolinska Institutet has today decided to award the 2016 Nobel Prize in Physiology or Medicine to Yoshinori Ohsumi for his discoveries of mechanisms for autophagy This year's Nobel Laureate discovered and elucidated mechanisms underlying Thus,autophagy denotes "self eating".
This concept emerged during the 1960's, when researchers first observed that the cell could destroy its own contents by enclosing it in membranes, forming sack-like vesicles that were transported to a recycling compartment, called the for degradation.
T-type Ca2 channels facilitate NO-formation, vasodilatation and NO-mediated modulation of blood pressure Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion Large-scale analysis of posttranslational modifications in the hippocampus of patients with Alzheimer's disease using p I shift and label-free quantification without enrichment Director SHIN Hee-Sup Doctor Shin is the director of the Center for Cognition and Sociality, established in July 2012. The thalamocortical circuit is a key component in regulating consciousness.
from Seoul National University before getting his Ph. In 2001 he became a principal research scientist at the Korea Institute of Science and Technology before taking up his position in IBS.
The Belgian scientist Christian de Duve was awarded the Nobel Prize in Physiology or Medicine in 1974 for the discovery of the lysosome.
New observations during the 1960's showed that large amounts of cellular content, and even whole organelles, could sometimes be found inside lysosomes.
Determining the precise processes by which lithium affects levels of serotonin in patients with bipolar disease may facilitate development of better therapies, and improved means for testing the effectiveness of these in targeting alterations in serotonin transmission.